中文   |   English   |   Email Alert

癌症化学预防:过去,现在和未来

Michael B. Sporn, Karen T. Liby

化学进展 ›› 2013, Vol. 25 ›› Issue (09) :1421-1428

PDF (2821KB)
化学进展 ›› 2013, Vol. 25 ›› Issue (09) :1421-1428 DOI: 10.7536/PC130409
癌症化学预防专辑
扫码查看或转发全文

癌症化学预防:过去,现在和未来

作者信息 +

A Mini-Review of Chemoprevention of Cancer——Past, Present, and Future

  • Michael B. Sporn*, Karen T. Liby
Author information +
文章历史 +

摘要

本文将对癌症化学预防的发展历史、研究现状及其未来前景作一简要评述,主要包括以下内容:癌症化学预防的科学基础,正在使用的癌症化学预防药物,对新合成药物的需求,以及面临的挑战等。本文尤其强调了联合用药在有效的癌症预防中的重要性。

Abstract

We present a brief review of the history of chemoprevention of cancer, the present status of this field, and its prospects for the future. Topics covered are the scientific basis for chemoprevention of cancer, drugs in current use for chemoprevention of cancer, the need for new synthetic drugs, and the challenges ahead. The importance of the use of combinations of drugs for effective prevention is stressed.

关键词

化学预防 / 癌症 / 选择性雌激素受体调控剂 / rexinoids / 三萜

Key words

chemoprevention / cancer / selective estrogen receptor modulators (SERM) / rexinoids / triterpenoids

引用本文

引用格式 ▾
Michael B. Sporn, Karen T. Liby. 癌症化学预防:过去,现在和未来[J]. 化学进展, 2013, 25(09): 1421-1428 DOI:10.7536/PC130409
A Mini-Review of Chemoprevention of Cancer——Past, Present, and Future[J]. Progress in Chemistry, 2013, 25(09): 1421-1428 DOI:10.7536/PC130409

登录浏览全文

4963

注册一个新账户 忘记密码

参考文献

[1] Bishop J M. Science, 1997, 278: 995
[2] Davidson N, Kensler T W. N. Engl. J. Med., 2011, 365: 2463—2464
[3] Sporn M B, Dunlop N M, Newton D L, Smith J M. Fed. Proc., 1976, 35: 1332—1338
[4] Sporn M B. Cancer Res., 1976, 36: 2699—2702
[5] Sporn M B. Lancet, 1996, 347: 1377—1381
[6] Sporn M B, Suh N. Nat. Rev. Cancer, 2002, 2: 537—543
[7] Sporn M B, Liby K T. Nat. Clin. Pract. Oncol., 2005, 2: 518—525
[8] Sporn M B. Nat. Clin. Pract. Oncol., 2006, 3: 364—373
[9] Albini A, Sporn M B. Nat. Rev. Cancer, 2007, 7: 139—147
[10] Liby K T, Yore M M, Sporn M B. Nat. Rev. Cancer, 2007, 7: 357—369
[11] Sporn M B. Nature, 2011, 471: S10—S11
[12] O'Shaughnessy J A, Kelloff G J, Gordon G B, Dannenberg A J, Hong W K, Fabian C J, Sigman C C, Bertagnolli M M, Stratton S P, Lam S, Nelson W G, Meyskens F L, Alberts D S, Follen M, Rustgi A K, Papadimitrakopoulou V, Scardino P T, Gazdar A F, Wattenberg L W, Sporn M B, Sakr W A, Lippman S M, von Hoff D D. Clin. Cancer Res., 2002, 8: 314—346
[13] Sporn M B. Cancer Res., 1991, 51: 6215—6218
[14] Hruban R H, Goggins M, Parsons J, Kern S E. Clin. Cancer Res., 2000, 6: 2969—2972
[15] Hingorani S R, Wang L, Multani A S, Combs C, Deramaudt T B, Hruban R H, Rustgi A K, Chang S, Tuveson D A. Cancer Cell, 2005, 7: 469—483
[16] Hingorani S R, Petricoin E F, Maitra A, Rajapakse V, King C, Jacobetz M A, Ross S, Conrads T P, Veenstra T D, Hitt B A, Kawaguchi Y, Johann D, Liotta L A, Crawford H C, Putt M E, Jacks T, Wright C V, Hruban R H, Lowy A M, Tuveson D A. Cancer Cell, 2003, 4: 437—450
[17] Pleasance E D, Stephens P J, O'Meara S, McBride D J, Meynert A, Jones D, Lin M L, Beare D, Lau K W, Greenman C, Varela I, Nik-Zainal S, Davies H R, Ordoñez G R, Mudie L J, Latimer C, Edkins S, Stebbings L, Chen L, Jia M, Leroy C, Marshall J, Menzies A, Butler A, Teague J W, Mangion J, Sun Y A, McLaughlin S F, Peckham H E, Tsung E F, Costa G L, Lee C C, Minna J D, Gazdar A, Birney E, Rhodes M D, McKernan K J, Stratton M R, Futreal P A, Campbell P J. Nature, 2010, 463: 184—190
[18] Sporn M B. Nature, 1980, 287: 107—108
[19] Meyskens F L Jr, McLaren C E, Pelot D, Fujikawa-Brooks S, Carpenter P M, Hawk E, Kelloff G, Lawson M J, Kidao J, McCracken J, Albers C G, Ahnen D J, Turgeon D K, Goldschmid S, Lance P, Hagedorn C H, Gillen D L, Gerner E W. Cancer Prev. Res., 2008, 1: 32—38
[20] Rendi M H, Suh N, Lamph W W, Krajewski S, Reed J C, Heyman R A, Berchuck A, Liby K, Risingsong R, Royce D B, Williams C R, Sporn M B. Cancer Res., 2004, 64: 3566—3571
[21] Tran K, Risingsong R, Royce D B, Williams C R, Sporn M B,Pioli P A, Gediya L K, Njar V C, Liby K T. Carcinogenesis, 2013, 34: 199—210
[22] Solomon S D, McMurray J J, Pfeffer M A, Wittes J, Fowler R, Finn P, Anderson W F, Zauber A, Hawk E, Bertagnolli M. N. Engl. J. Med., 2005, 352: 1071—1080
[23] Bresalier R S, Sandler R S, Quan H, Bolognese J A, Oxenius B, Horgan K, Lines C, Riddell R, Morton D, Lanas A, Konstam M A, Baron J A. N. Engl. J. Med., 2005, 352: 1092—1102
[24] Wu X, Lippman S M. Nat. Rev. Cancer, 2011, 11: 879—885
[25] LaCroix A Z, Powles T, Osborne C K, Wolter K, Thompson J R, Thompson D D, Allred D C, Armstrong R, Cummings S R, Eastell R, Ensrud K E, Goss P, Lee A, Neven P, Reid D M, Curto M, Vukicevic S. J. Natl. Cancer Inst., 2010, 102: 1706—1715
[26] Andriole G L, Bostwick D G, Brawley O W, Gomella L G, Marberger M, Montorsi F, Pettaway C A, Tammela T L, Teloken C, Tindall D J, Somerville M C, Wilson T H, Fowler I L, Rittmaster R S. N. Engl. J. Med., 2010, 362: 1192—1202
[27] Chan A T. Prog. Chem., 2013, 25: 1450—1453
[28] Decensi A, Puntoni M, Goodwin P, Cazzaniga M, Gennari A, Bonanni B, Gandini S. Cancer Prev. Res. (Phila), 2010, 3: 1451—1461
[29] Umar A, Dunn B K, Greenwald P. Nature Reviews Cancer, 2012, 12: 835—848
[30] Egner P A, Wang J B, Kensler T W, et al. Prog. Chem., 2013, 25: 1454—1461
[31] Sporn M B, Liby K T, Yore M M, Suh N, Albini A, Honda T, Sundararajan C, Gribble G W. Drug Dev. Res., 2007, 68: 174—182
[32] Sporn M B, Liby K T, Yore M M, Fu L, Lopchuk J M, Gribble G W. J. Nat. Prod., 2011, 74: 537—545
[33] Liby K T, Sporn M B. Pharmacol. Revs., 2012, 64: 972—1003
[34] Liby K, Royce D B, Williams C R, Risingsong R, Yore M M, Honda T, Gribble G W, Dmitrovsky E, Sporn T A, Sporn M B. Cancer Res., 2007, 67: 2414—2419
[35] Yore M M, Kettenbach A N, Sporn M B, Gerber S A, Liby K T. PLoS One, 2011, 6: 22862—22863
[36] Hong D S, Kurzrock R, Supko J G, He X, Naing A, Wheler J, Lawrence D, Eder J P, Meyer C J, Ferguson D A, Mier J, Konopleva M, Konoplev S, Andreeff M, Kufe D, Lazarus H, Shapiro G I, Dezube B J. Clin. Cancer Res., 2012, 18: 3396—3406
[37] Foulds L. Neoplastic Development. London ; New York: Academic P. 1969. 269
[38] Clark W H Jr. Acta Oncol., 1995, 34: 3—21
[39] Bissell M J, Hines W C. Nat. Med., 2011, 17: 320—329
[40] Coussens L M, Zitvogel L, Palucka A K. Science, 2013, 339: 286—291
[41] Albini A, Tosetti F, Li V W, Noonan D M, Li W W. Nat. Rev. Clin. Oncol., 2012, 9: 498—509
[42] Dawson M A, Kouzarides T. Cell, 2012, 150: 12—27
[43] Huang Y W, Kuo C T, Stoner K, Huang T H, Wang L S. FEBS Lett., 2011, 585: 2129—2136
[44] Lee J H, Khor T O, Shu L, Su Z Y, Fuentes F, Kong A N. Pharmacol. Ther., 2013, 137(2): 153—171
[45] Guttman M, Amit I, Garber M, French C, Lin M F, Feldser D, Huarte M, Zuk O, Carey B W, Cassady J P, Cabili M N, Jaenisch R, Mikkelsen T S, Jacks T, Hacohen N, Bernstein B E, Kellis M, Regev A, Rinn J L, Lander E S. Nature, 2009, 458: 223—227
[46] Lee J T. Science, 2012, 338: 1435—1439
[47] You J S, Jones P A. Cancer Cell, 2012, 22: 9—20
[48] Tsai H C, Baylin S B. Cell Res., 2011, 21: 502—517
[49] Gerlinger M, Rowan A J, Horswell S, Larkin J, Endesfelder D, Gronroos E, Martinez P, Matthews N, Stewart A, Tarpey P, Varela I, Phillimore B, Begum S, McDonald N Q, Butler A, Jones D, Raine K, Latimer C, Santos C R, Nohadani M, Eklund A C, Spencer-Dene B, Clark G, Pickering L, Stamp G, Gore M, Szallasi Z, Downward J, Futreal P A, Swanton C. N. Engl. J. Med., 2012, 366: 883—892
[50] Swanton C. Cancer Res., 2012, 72: 4875—4882
[51] Longo D L. N. Engl. J. Med., 2012, 366: 956—957
[52] Hopkins A L. Nat. Biotechnol., 2007, 25: 1110—1111
[53] Barabasi A L. Linked: How Everything is Connected to Everything Else and What it Means. New York: Penguin Group, 2000
[54] Prevention of Cancer in the Next Millennium: Report of the Chemoprevention Working Group to the American Association for Cancer Research. Cancer Res., 1999, 59: 4743—4758
[55] Levy E D, Landry C R, Michnick S W. Science, 2010, 328: 983—984

PDF (2821KB)

2770

访问

0

被引

详细

导航
相关文章

/

〈 〉