微生物电化学系统电子中介体

刘利丹; 肖勇; 吴义诚; 陈必链; 赵峰

doi:10.7536/PC140740

化学进展 ›› 2014, Vol. 26 ›› Issue (11) :1859-1866 DOI: 10.7536/PC140740

综述与评论

扫码查看或转发全文

微生物电化学系统电子中介体

^1,2

^2,3

作者信息 +

Electron Transfer Mediators in Microbial Electrochemical Systems

Liu Lidan^1,2, Xiao Yong*², Wu Yicheng^2,3, Chen Bilian*¹, Zhao Feng²

Author information +

文章历史 +

摘要

电化学活性微生物与电极之间的胞外电子传递在微生物电化学系统(microbial electrochemical systems,MESs)产能、生物修复等功能的实现中起着关键作用.目前,研究者对微生物胞外电子传递机理了解有限,限制了MESs的应用.相比于需要微生物功能蛋白与电极接触才能发生的直接电子传递,间接电子传递可通过具有可逆氧化还原活性的电子中介体(electron transfer mediators,ETMs)实现电子的传递,从而有效提高微生物胞外电子传递效率.在间接电子转移过程中,ETMs起着中间电子受体和中间电子供体的作用,即被还原后可将电子传递给最终电子受体并被重新还原;理论上每个ETMs分子可以循环数千次,因此ETMs对特定环境下终端氧化物(如铁离子)的循环有着极其显著的作用.本文系统总结了MESs中ETMs及间接电子传递机制近年来的研究进展,并且在此基础上探讨了ETMs在MESs中的研究趋势,以期推动MESs在生物修复、能源生产方面的实际应用.

Abstract

Extracellular electron transfer (EET) between electrochemically active microorganisms and electrodes plays a key role in microbial electrochemical systems (MESs) functioning of energy generation, bioremediation, etc. At present, researchers have a very limited understanding of the mechanism of EET, which is one of the major bottlenecks in application of MESs. Compared with direct electron transfer which requires a direct contact between microbial functional proteins and electrode, mediated electron transfer use electron transfer mediators (ETMs) which have reversible redox activities accompanies by high-efficiency EET for transporting electrons. ETMs serve as the middle electron acceptor, once reduced, can transfer electrons to terminal electron acceptor where upon it becomes re-oxidized. In principle, ETMs molecules could cycle thousands of times,thus, have a significant effect on the turnover of the terminal oxidant (e.g.iron) in certain circumstances.This review summarizes the recent advances of EET mechanisms with focus on mediated EET in MESs. Furthermore, we have highlighted the research trends of ETMs in MES,which will promote the practical applications of MESs in bioremediation, energy generation and so on.

Contents
1 Introduction
2 Roles of electron transfer mediators in extracellular electron transfer
3 Properties of electron transfer mediators
4 Classification of electron transfer mediators
5 Electron transfer mediators and their electron transfer mechanism
5.1 Exogenous electron transfer mediators
5.2 Endogenous electron transfer mediators
6 Outlook

Graphical abstract

关键词

微生物电化学系统 / 胞外电子传递 / 间接电子传递 / 电子中介体 / 吩嗪 / 核黄素

Key words

microbial electrochemical systems / extracellular electron transfer / mediated electron transfer / electron transfer mediators / phenazines / flavins

引用本文

引用格式 ▾

刘利丹, 肖勇, 吴义诚, 陈必链, 赵峰. 微生物电化学系统电子中介体[J]. 化学进展, 2014, 26(11): 1859-1866 DOI:10.7536/PC140740

Liu Lidan, Xiao Yong, Wu Yicheng, Chen Bilian, Zhao Feng. Electron Transfer Mediators in Microbial Electrochemical Systems[J]. Progress in Chemistry, 2014, 26(11): 1859-1866 DOI:10.7536/PC140740

登录浏览全文

4963

注册一个新账户忘记密码

参考文献

原文顺序 | 出版日期 | 本文引用

[1] Bond D R, Holmes D E, Tender L M, Lovley D R. Science, 2002, 295: 483.
[2] Lovley D R. Nat. Rev. Microbiol., 2006, 4: 797.
[3] Antonopoulou G, Stamatelatou K, Bebelis S, Lyberatos G. Biochem. Eng. J., 2010, 50: 10.
[4] Liu Z D, Li H R. Biochem. Eng. J., 2007, 36: 209.
[5] Lovley D R. Curr. Opin. Biotechnol., 2008, 19: 564.
[6] Hosseini M G, Ahadzadeh I. J. Power Sources, 2012, 220: 292.
[7] Brutinel E D, Gralnick J A. Appl. Microbiol. Biotechnol., 2012, 93: 41.
[8] 肖勇(Xiao Y), 吴松(Wu S), 杨朝晖(Yang Z H), 郑越(Zheng Y), 赵峰(Zhao F). 化学进展(Progress in Chemistry), 2013, 25: 1771.
[9] Deng L, Li F, Zhou S, Huang D, Ni J. Chin. Sci. Bull., 2010, 55: 99.
[10] Velasquez-Orta S B, Head I M, Curtis T P, Scott K, Lloyd J R, von Canstein H. Appl. Microbiol. Biotechnol., 2010, 85: 1373.
[11] Bond D R, Lovley D R. Appl. Environ. Microbiol., 2003, 69: 1548.
[12] Chaudhuri S K, Lovley D R. Nat. Biotechnol., 2003, 21: 1229.
[13] Reguera G, Mccarthy K D, Mehta T, Nicoll J S, Tuominen M T, Lovley D R. Nature, 2005, 435: 1098.
[14] Schroder U. Phys. Chem. Chem. Phys., 2007, 9: 2619.
[15] Kotloski N J, Gralnick J A. mBio, 2013, 4: e00553
[16] Lovley D R. Annu. Rev. Microbiol., 2012, 66: 391.
[17] Logan B E, Hamelers B, Rozendal R A, Schrorder U, Keller J, Freguia S, Aeiterman P, Verstraete W, Rabaey K. Environ. Sci. Technol., 2006, 40: 5181.
[18] Taskan E, Özkaya B, Hasar H. Int. J. Energ. Sci., 2014, 4: 9.
[19] Hao M, Liu X, Feng M, Zhang P, Wang G. J. Power Sources, 2014, 251: 222.
[20] Wang Y, Newman D K. Environ. Sci. Technol., 2008, 42: 2380.
[21] Marsili E, Baron D B, Shikhare I D, Coursolle D, Gralnick J A, Bond D R. Proc. Natl. Acad. Sci. U.S.A., 2008, 105: 3968.
[22] Rabaey K, Boon N, Hofte M, Verstraete W. Environ. Sci. Technol., 2005, 39: 3401.
[23] Watanabe K, Manefield M, Lee M, Kouzuma A. Curr. Opin. Biotechnol., 2009, 20: 633.
[24] Martinez C M, Alvarez L H, Cervantes F J. Biodegradation, 2012, 23: 635.
[25] Bae S, Lee Y, Kwon M J, Lee W. J. Hazard. Mater., 2014, 274: 24.
[26] Yamazaki S, Kano K, Ikeda T, Isawa K, Kaneko T. BBA-Gen Subjects, 1999, 1428: 241.
[27] Kazarinov I A, Ignatova A A, Naumova M N. Russ. J. Electrochem., 2014, 50: 87.
[28] Van Der Zee F R, Cervantes F J. Biotechnol. Adv., 2009, 27: 256.
[29] Yang Y G, Xu M Y, Guo J, Sun G P. Process Biochem., 2012, 47: 1707.
[30] Stams A J M, de Bok F A M, Plugge C M, van Eekert M H A, Dolfing J, Schraa G. Environ. Microbiol., 2006, 8: 371.
[31] Zachara J M, Kukkadapu R K, Peretyazhko T, Bowden M, Wang C M, Kennedy D W, Moore D, Arey B. Geochim. Cosmochim. Acta, 2011, 75: 6330.
[32] Shi Z, Zachara J M, Shi L, Wang Z M, Moore D A, Kennedy D W, Fredrickson J K. Environ. Sci. Technol., 2012, 46: 11644.
[33] Aulenta F, Di Maio V, Ferri T, Majone M. Bioresour. Technol., 2010, 101: 9728.
[34] McKinlay J B, Zeikus J G. Appl. Environ. Microbiol., 2004, 70: 3467.
[35] Sun Y, Shao Y, Peng J, Liu L, Teng B. Sensor. Actuat. B-Chem., 2013, 188: 242.
[36] Park D H, Zeikus J G. Appl. Environ. Microbiol., 2000, 66: 1292.
[37] Chen H, Zhao J, Dai G. J. Hazard. Mater., 2011, 186: 1320.
[38] Sund C J, McMasters S, Crittenden S R, Harrell L E, Sumner J J. Appl. Microbiol. Biotechnol., 2007, 76: 561.
[39] Bhattacharyya A, Stavitski E, Dvorak J, Martínez C E. Geochim. Cosmochim. Acta, 2013, 122: 89.
[40] Kaden J, Galushko A S, Schink B. Arch. Microbiol., 2002, 178: 53.
[41] Ruan C M, Yang F, Lei C H, Deng J Q. Anal. Chem., 1998, 70: 1721.
[42] Wang Y, Kern S E, Newman D K. J. Bacteriol., 2010, 192: 365.
[43] Yamazki S, Kaneko T, Taketomo N, Kano K, Ikeda T. Appl. Microbiol. Biotechnol., 2002, 59: 72.
[44] Wang Y F, Masuda M, Tsujimura S, Kano K. Biotechnol. Bioeng., 2008, 101: 579.
[45] Marsili E, Baron D B, Shikhare I D, Coursolle D, Gralnick J A, Bond D R. Proc. Natl. Acad. Sci. U.S.A., 2008, 105: 3968.
[46] Newman D K, Kolter R. Nature, 2000, 405: 94.
[47] Lovley D R, Coates J D, Bluntharris E L, Phillips E J P, Woodward J C. Nature, 1996, 382: 445.
[48] Coates J D, Cole K A, Chakraborty R, O'connor S M, Achenbach L A. Appl. Environ. Microbiol., 2002, 68: 2445.
[49] Hernandez-Montoya V, Alvarez L H, Montes-Moran M A, Cervantes F J. Geoderma, 2012, 183: 25.
[50] Wu C Y, Zhuang L, Zhou S G, Yuan Y, Yuan T, Li F B. Microb. Biotechnol., 2013, 6: 141.
[51] Klupfel L, Piepenbrock A, Kappler A, Sander M. Nat. Geosci., 2014, 7: 195.
[52] Cory R M, McKnight D M. Environ. Sci. Technol., 2005, 39: 8142.
[53] Mueller R M, North M A, Hati C Y S, Bhattacharyya S. J. Phys. Chem. B, 2011, 115: 3632.
[54] Zhang C, Katayama A. Environ. Sci. Technol., 2012, 46: 6575.
[55] Hong Y, Wu P, Li W, Gu J, Duan S. Appl. Microbiol. Biotechnol., 2012, 93: 2661.
[56] Liu G F, Zhou J T, Ji Q Y, Wang J, Jin R F, Lv H. World. J. Microb. Biot., 2013, 29: 1723.
[57] Shimizu T. J. Inorg. Biochem., 2012, 108: 171.
[58] Min B K, Cheng S A, Logan B E. Water Res., 2005, 39: 1675.
[59] Maithreepala R A, Doong R A. J. Hazard. Mater., 2009, 164: 337.
[60] Liu D, Dong H, Zhao L, Wang H. Geomicrobiol. J., 2013, 31: 53.
[61] Nevin K P, Lovley D R. Environ. Sci. Technol., 2000, 34: 2472.
[62] Zhang G, Burgos W D, Senko J M, Bishop M E, Dong H, Boyanov M I, Kemner K M. Chem. Geol., 2011, 283: 242.
[63] Hosseini M G, Ahadzadeh I. J. Taiwan. Inst. Chem. E, 2013, 44: 617.
[64] Wang K P, Liu Y W, Chen S L. J. Power Sources, 2011, 196: 164.
[65] Liu X W, Sun X F, Chen J J, Huang Y X, Xie J F, Li W W, Sheng G P, Zhang Y Y, Zhao F, Lu R, Yu H Q. Sci. Rep., 2013, 3: 1616.
[66] Rahimnejad M, Najafpour G D, Ghoreyshi A A, Talebnia F, Premier G C, Bakeri G, Kim J R, Oh S E. J. Microbiol., 2012, 50: 575.
[67] Liu R H, Sheng G P, Sun M, Zang G L, Li W W, Tong Z H, Dong F, Lam M H, Yu H Q. Appl. Microbiol. Biotechnol., 2011, 89: 201.
[68] Ahuja E G, Janning P, Mentel M, Graebsch A, Breinbauer R, Hiller W, Costisella B, Thomashow L S, Mavrodi D V, Blankenfeldt W. J. Am. Chem. Soc., 2008, 130: 17053.
[69] Das T, Manefield M. Commun. Integr. Biol., 2013, 6: e23570
[70] Venkataraman A, Rosenbaum M, Arends J B A, Halitschke R, Angenent L T. Electrochem. Commun., 2010, 12: 459.
[71] Abken H J, Tietze M, Brodersen J, Baumer S, Beifuss U, Deppenmeier U. J. Bacteriol., 1998, 180: 2027.
[72] Hernandez M E, Kappler A, Newman D K. Appl. Environ. Microbiol., 2004, 70: 921.
[73] Rabaey K, Boon N, Hofte M, Verstraete W. Environ. Sci. Technol., 2005, 39: 3401.
[74] Pham T H, Boon N, Aelterman P, Clauwaert P, De Schamphelaire L, Vanhaecke L, De Maeyer K, Hofte M, Verstraete W, Rabaey K. Appl. Microbiol. Biotechnol., 2008, 77: 1119.
[75] Yong Y C, Yu Y Y, Li C M, Zhong J J, Song H. Biosens. Bioelectron., 2011, 30: 87.
[76] Wang V B, Chua S L, Cao B, Seviour T, Nesatyy V J, Marsili E, Kjelleberg S, Givskov M, Tolker-Nielsen T, Song H, Say J, Loo C, Yang L. PLoS One, 2013, 8: e63129.
[77] Yong X Y, Shi D Y, Chen Y L, Feng J, Xu L, Zhou J, Wang S Y, Yong Y C, Sun Y M, Ouyang P K, Zheng T. Bioresour. Technol., 2014, 152: 220.
[78] Chen J J, Chen W, He H, Li D B, Li W W, Xiong L, Yu H Q. Environ. Sci. Technol., 2013, 47: 1033.
[79] North M A, Bhattacharyya S, Truhlar D G. J. Phys. Chem. B, 2010, 114: 14907.
[80] Tan S L J, Webster R D. J. Am. Chem. Soc., 2012, 134: 5954.
[81] Wu C, Cheng Y Y, Li B B, Li W W, Li D B, Yu H Q. Bioresour. Technol., 2013, 136: 711.
[82] Baron D, Labelle E, Coursolle D, Gralnick J A, Bond D R. J. Biol. Chem., 2009, 284: 28865.
[83] Von Canstein H, Ogawa J, Shimizu S, Lloyd J R. Appl. Environ. Microbiol., 2008, 74: 615.
[84] Bae S, Lee W. Geochim. Cosmochim. Acta, 2013, 114: 144.
[85] Fuller S J, McMillan D G G, Renz M B, Schmidt M, Burke I T, Stewart D I. Appl. Environ. Microbiol., 2014, 80: 128.
[86] Okamoto A, Hashimoto K, Nealson K H, Nakamura R. Proc. Natl. Acad. Sci. U.S.A., 2013, 110: 7856.
[87] Okamoto A, Saito K, Inoue K, Nealson K H, Hashimoto K, Nakamura R. Energ. Environ. Sci., 2014, 7: 1357.
[88] Le Laz S, Kpebe A, Lorquin J, Brugna M, Rousset M. Appl. Microbiol. Biotechnol., 2014, 98: 2699.
[89] Keck A, Klein J, Kudlich M, Stolz A, Knackmuss H J, Mattes R. Appl. Environ. Microbiol., 1997, 63: 3684.
[90] Keck A, Rau J, Reemtsma T, Mattes R, Stolz A, Klein J. Appl. Environ. Microbiol., 2002, 68: 4341.
[91] Lu H, Zhou J, Wang J, Si W, Teng H, Liu G. Bioresour. Technol., 2010, 101: 7196.
[92] Deng L F, Li F B, Zhou S G, Huang D Y, Ni J R. Chin. Sci. Bull., 2010, 55: 99.
[93] Freguia S, Masuda M, Tsujimura S, Kano K. Bioelectrochemistry, 2009, 76: 14.
[94] Crippa P R, Michelini S. J. Photoch. Photobio. B, 1999, 50: 119.
[95] Plonka P M, Grabacka M. Acta Biochim. Pol., 2006, 53: 429.
[96] Turick C E, Caccavo F, Tisa L S. Can. J. Microbiol., 2008, 54: 334.
[97] Bothma J P, De Boor J, Divakar U, Schwenn P E, Meredith P. Adv. Mater., 2008, 20: 3539.
[98] Sajjan S S, Korean J. Microbiol. Biotechnol., 2013, 41: 60.
[99] Turick C E, Caccavo F, Tisa L S. FEMS Microbiol. Lett., 2003, 220: 99.
[100] Chatfield C H, Cianciotto N P. Infect. Immun., 2007, 75: 4062.
[101] Turick C E, Beliaev A S, Zakrajsek B A, Reardon C L, Lowy D A, Poppy T E, Maloney A, Ekechukwu A A. FEMS Microbiol. Ecol., 2009, 68: 223.
[102] Williams J, Trautwein-Schult A, Jankowska D, Kunze G, Squire M A, Baronian K. Appl. Microbiol. Biotechnol., 2014, 98: 2223.
[103] Cao X X, Huang X, Boon N, Liang P, Fan M Z. Electrochem. Commun., 2008, 10: 1392.
[104] Xiang K J, Qiao Y, Ching C B, Li C M. Electrochem. Commun., 2009, 11: 1593.
[105] Kim E, Gordonov T, Bentley W E, Payne G F. Anal. Chem., 2013, 85: 2102.
[106] Ding C M, Liu H, Zhu Y, Wan M X, Jiang L. Energ. Environ. Sci., 2012, 5: 8517.
[107] Liu J, Qiao Y, Lu Z S, Song H, Li C M. Electrochem. Commun., 2012, 15: 50.
[108] Yong Y C, Yu Y Y, Yang Y, Liu J, Wang J Y, Song H. Biotechnol. Bioeng., 2013, 110: 408.ich M, Stolz A, Knackmuss H J, Mattes R. Appl. Environ. Microbiol., 1997, 63: 3684.
[90] Keck A, Rau J, Reemtsma T, Mattes R, Stolz A, Klein J. Appl. Environ. Microbiol., 2002, 68: 4341.
[91] Lu H, Zhou J, Wang J, Si W, Teng H, Liu G. Bioresour. Technol., 2010, 101: 7196.
[92] Deng L F, Li F B, Zhou S G, Huang D Y, Ni J R. Chin. Sci. Bull., 2010, 55: 99.
[93] Freguia S, Masuda M, Tsujimura S, Kano K. Bioelectrochemistry, 2009, 76: 14.
[94] Crippa P R, Michelini S. J. Photoch. Photobio. B., 1999, 50: 119.
[95] Plonka P M, Grabacka M. Acta Biochim. Pol., 2006, 53: 429.
[96] Turick C E, Caccavo F, Tisa L S. Can. J. Microbiol., 2008, 54: 334.
[97] Bothma J P, De Boor J, Divakar U, Schwenn P E, Meredith P. Adv. Mater., 2008, 20: 3539.
[98] Sajjan S S. Korean. J. Microbiol. Biotechnol., 2013, 41: 60.
[99] Turick C E, Caccavo F, Tisa L S. FEMS Microbiol. Lett., 2003, 220: 99.
[100] Chatfield C H, Cianciotto N P. Infect. Immun, 2007, 75: 4062.
[101] Turick C E, Beliaev A S, Zakrajsek B A, Reardon C L, Lowy D A, Poppy T E, Maloney A, Ekechukwu A A. FEMS Microbiol. Ecol., 2009, 68: 223.
[102] Williams J, Trautwein-Schult A, Jankowska D, Kunze G, Squire M A, Baronian K. Appl. Microbiol. Biotechnol., 2014, 98: 2223.
[103] Cao X X, Huang X, Boon N, Liang P, Fan M Z. Electrochem. Commun., 2008, 10: 1392.
[104] Xiang K J, Qiao Y, Ching C B, Li C M. Electrochem. Commun., 2009, 11: 1593.
[105] Kim E, Gordonov T, Bentley W E, Payne G F. Anal. Chem., 2013, 85: 2102.
[106] Ding C M, Liu H, Zhu Y, Wan M X, Jiang L. Energ. Environ. Sci., 2012, 5: 8517.
[107] Liu J, Qiao Y, Lu Z S, Song H, Li C M. Electrochem. Commun., 2012, 15: 50.
[108] Yong Y C, Yu Y Y, Yang Y, Liu J, Wang J Y, Song H. Biotechnol. Bioeng., 2013, 110: 408.