A Mini-Review of Chemoprevention of Cancer——Past, Present, and Future

Michael B. Sporn, Karen T. Liby

doi:10.7536/PC130409

Progress in Chemistry ›› 2013, Vol. 25 ›› Issue (09) : 1421-1428 DOI: 10.7536/PC130409

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A Mini-Review of Chemoprevention of Cancer——Past, Present, and Future

Michael B. Sporn, Karen T. Liby

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Abstract

We present a brief review of the history of chemoprevention of cancer, the present status of this field, and its prospects for the future. Topics covered are the scientific basis for chemoprevention of cancer, drugs in current use for chemoprevention of cancer, the need for new synthetic drugs, and the challenges ahead. The importance of the use of combinations of drugs for effective prevention is stressed.

Keywords

chemoprevention / cancer / selective estrogen receptor modulators (SERM) / rexinoids / triterpenoids

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Michael B. Sporn, Karen T. Liby. A Mini-Review of Chemoprevention of Cancer——Past, Present, and Future. Progress in Chemistry, 2013, 25(09): 1421-1428 DOI:10.7536/PC130409