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Synthesis and Biological Activity of Steroids Bearing Aromatic Rings and Heterocycles

Cui Jianguo, Liu Liang, Gan Chunfang, Xiao Qi, Huang Yanmin

Progress in Chemistry ›› 2014, Vol. 26 ›› Issue (0203) : 320 -333.

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Progress in Chemistry ›› 2014, Vol. 26 ›› Issue (0203) : 320-333 DOI: 10.7536/PC130652
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Synthesis and Biological Activity of Steroids Bearing Aromatic Rings and Heterocycles
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Abstract

Steroids bearing aromatic rings and heterocycles are types of compounds with significant physiological activities. Generally, they possess a good antibacterial, anti-inflammatory and anti-tumor activity. In this paper, the synthesis and biological activity of steroids bearing aromatic rings and heterocycles in recent year are reviewed according to the classification of their structures, such as steroidal heterocycles bonded A-ring, fused A-ring, bonded B-ring, bonded D-ring, etc. Their developing trends and applying prospects are also expected.

Contents
1 Steroids bearing aromatic rings and heterocycles bonded A-ring
2 Steroids bearing aromatic rings and heterocycles fused A-ring
3 Steroids bearing aromatic rings and heterocycles bonded B-ring
4 Steroids bearing aromatic rings and heterocycles bonded D-ring
4.1 Steroids bearing aromatic rings and heterocycles bonded 17-C
4.2 Steroids bearing aromatic rings and heterocycles bonded 16-C
5 Steroids bearing aromatic rings and heterocycles fused D-ring
6 Outlook

Keywords

steroids bearing aromatic ring and heterocycle / biological activity / anti-tumor activity

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Cui Jianguo, Liu Liang, Gan Chunfang, Xiao Qi, Huang Yanmin. Synthesis and Biological Activity of Steroids Bearing Aromatic Rings and Heterocycles. Progress in Chemistry, 2014, 26(0203): 320-333 DOI:10.7536/PC130652

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