Proteins possess versatile function and unique structure, and show the distinguished self-assembly feature. Polypeptide chains with the determined amino acid sequence are formed through amide bond and considered as the primary building blocks of protein. The weak intermolecular interactions of polypeptide chains control the folding of the polypeptide chains and high-level structure of protein. In addition, proteins are a class of renewable resources and show biodegradable and biocompatible. Using the self-assembly feature of protein is the potential strategy for fabricate the controlled self-assembly system with biofunctional in the field of nanoscience, materials and biomedical and so on. Hence, the present review describes the self-assembly feature of protein from the chemical point of view. The self-assembly of heat-denatured protein, metal-induced self-assembly of protein, self-assembly of protein with polymer and self-assembly of protein hybrids are further explored. The goal of this review is to further learn and understand the self-assembly feature of protein, and provide ideas for designing and fabricating the controlled structural self-assembly systems with unique function.

Contents
1 Introduction
2 Self-assembly feature of protein structure
3 Self-assembly of denatured protein
4 Metal-induced self-assembly of protein
5 Self-assembly of polymer with protein
6 Self-assembly of protein-polymer hybrid
7 Conclusions and outlook