Organosilicon, as one of the most popular softeners in the textile industry, not only can impart unique softness, smoothness, elasticity and silk-and cotton-like hands to treated fabrics, but also confer the fabrics with a perfect drape, anti-wrinkle, wettability and breathability. In recent years, with the widespread of highly pathogenic microorganism and viruses, people pay more and more attention to the antibacterial finishing of fabric. Moreover,the antibacterial finishing agent is also thought to be one of the most promising finishing agent. So a large number of organosilicon antimicrobial agents were prepared though chemical grafting or physical blending of the microbicides and organic silicon. Relevant researches have been becoming active and some important achievements have been made. The review systematically summarized the recent advances in the synthesis and antimicrobial effect of organosilicon quaternary ammonium salts, N-halamine compounds, organosilicon with antimicrobial inorganic materials and so on. What is more, the mechanism of organosilicon antimicrobial agents is briefly introduced in three aspects: targeting on microbial cell wall, cell membranes, restraining biosynthesis of protein and nucleic acid. Finally, based on the analysis of the present situation of antibacterial finishing agent, the ideal characteristics of antibacterial finishing agent come forward. Besides, the development and application prospect of antibacterial finishing agent are discussed.

Contents
1 Introduction
2 The classification of organosilicon antimicrobial agent(OSAA)
2.1 Organosilicon quaternary ammonium salts
2.2 Regenerable N-halamine compounds
2.3 Organosilicon with antimicrobial inorganic materials
2.4 Others
3 The Mechanism of OSAA
3.1 The OSAA target cell wall synthesis
3.2 The OSAA target cell membrane synthesis
3.3 The OSAA inhibit or interfere with microbial nucleic acid and protein synthesis
4 Prospect