Per- and polyfluoroalkyl substances (PFASs) are widely used in numerous industrial and commercial products due to their unique hydrophobic, oil-repellence and high surface activity. In recent years they have been detected in various environmental matrix and become the widespread organic pollutants. Based on their ubiquitous distribution, persistence and bioaccumulation, the per- and polyfluoroalkyl substances have attracted remarkable attention from related scientists and organizations. The fourth meeting of the Conference of the Parties of the Stockholm Convention (SC) on Persistent Organic Pollutants (POPs) held at the Geneva in May, 2009, has decided to place perfluorooctane sulfonic acid, its salts and perfluorooctane sulfonyl fluoride into Annex B of the convention. From then on, the perfluorinated chemicals as new emerging contaminants, have received great attention, and the research about their environmental problems has come to a new stage of development. This paper reviews the research progress on the analytical method, environmental distribution and behavior, bioaccumulation and biomagnification, human exposure and healthy effect, emerging analogues of PFASs. The emphasis be laid on the advances achieved after perfluorooctane sulfonic acid, its salts and perfluorooctane sulfonyl fluoride were listed into Anne

Contents
1 Introduction
2 Analytical method
3 Environmental distribution and behavior
4 Bioaccumulation and biomagnification
5 Human exposure and health effects
6 Emerging analogues of per- and polyfluorinated chemicals
7 Conclusion and outlook