The applications of the heterogeneous cyclodextrins in aqueous phase organic synthesis are reviewed in detail, including the applications in oxidation, reduction, substitution reaction, addition reaction and photocatalytic reaction. At the same time, the strategies to construct heterogeneous cyclodextrins in the catalysis or promotion of the aqueous phase organic synthesis are stated comprehensively, two strategies being the formation of water-insoluble cross-linking polymer and the grafting cyclodextrins to water-insoluble supporter. It is pointed out that the application of the heterogeneous cyclodextrins in aqueous phase organic synthesis is limited in the simple phase-transfer catalysis and there is fewer relevant literature, just in its infancy stage. The construction of artificial enzyme based on the heterogeneous cyclodextrins would be the development trend and inevitable affiliation in the construction of artificial enzyme based on cyclodextrins, possessing the advantage of the heterogeneous catalyst, meanwhile retaining the excellent function of the cyclodextrin unit in the construction of supramolecular artificial enzyme.

Contents
1 Introduction
2 Oxidation Reaction
3 Reduction Reaction
4 Substitution Reaction
5 Addition Reaction
6 Photocatalytic Reaction
7 Conclusion and outlook