With the rapid development of supramolecular chemistry, the mechanically interlocked molecules based on N-hetero crown ethers (NHCE) have attracted increasing interest in recent years. Compared with the traditional synthetic methods, the templated clipping approach has unique advantages in constructing mechanically interlocked molecules based on NHCE, and many important advances have been obtained. Scientists have not only gradually expanded the topological structures of mechanically interlocked molecules based on NHCE, but also enriched their application in various regions. Herein, we summarize the progress of templated clipping approach in the structure construction of the mechanically interlocked molecules (such as rotaxanes, catenanes, heterorotaxanes, rotacatenanes, oligomers, daisy chains and dendritic molecules) and their potential applications.

Contents
1 Introduction
2 Rotaxanes based on NHCE
2.1 Oligorotaxanes
2.2 Rectangular rotaxanes
2.3 Dendritic rotaxanes
2.4 Heterorotaxanes
2.5 Functional rotaxanes
3 Catenanes based on NHCE
4 Rotaxane-fused-catenane integrations
5 Daisy chains based on NHCE
6 Conclusion