Study on the interaction of corrole and its metal complex with DNA and their anti-tumor activity has become one of the hot topics of corrole chemistry. This review covers the progress on the study of the interaction of corrole and its metal complex with DNA and their anti-tumor activity. The binding mode of corrole or its metal complex with DNA, chemical nuclease activity of corrole and its metal complex in the presence of oxidants or under irradiation, the interaction of corrole and its metal complex with G-quadruplex DNA and their anti-tumor activity are introduced systematically.

Contents
1 Introduction
2 Binding modes between corrole or its metal complex and DNA
3 Nuclease activity of corrole and its metal complex
3.1 Oxidative DNA cleavage mediated by metal corrole
3.2 Photocleavage of DNA by corrole and its metal complex
4 Interaction between G-quadruplex DNA and corrole or its metal complex
5 Anti-tumor activity of corrole and its metal complex
6 Conclusion