As one of the important parts of the molecular machines, molecular machines driven by acid-base chemistry play the crucial role in molecular machines, and have attracted more and more attentions for the applications in the design and construction of controllable molecular machines. At the same time, owing to the great progresses in theory studies of the molecular machine, several different kinds of functional and practical molecular machines driven by acid-base stimuli have been reported and utilized in supramolecular gels, supramolecular catalysts, supramolecular vesicles, supramolecular nanovalves, supramolecular polymers, and so on. In this paper, the design and applications of acid-base controllable molecular machines based on pseudorotaxanes, rotaxanes, and catenanes are reviewed, and the prospects of such molecular machines are also described.

Contents
1 Introduction
2 Molecular machines driven by acid-base chemistry
2.1 Acid-base driven molecular machines based on pseudorotaxanes
2.2 Acid-base driven rotaxanes-based molecular machines
2.3 Catenane-type molecular machines driven by acid-base stimuli
3 The applications of acid-base driven molecular machines
3.1 Supramolecular gel
3.2 Treatment of paraquat poisoning and supramolecular vesicles
3.3 Supramolecular catalysis
3.4 Supramolecular nanovalve
3.5 Supramolecular polymer
4 Conclusion and outlook