Pharmaceuticals and personal care products (PPCPs) as emerging organic contaminants are mostly chiral compounds. They are usually consumed as racemic compounds or single enantiomers. Biological degradation process can lead to stereoselective enrichment of enantiomer of chiral PPCPs. Due to the difficulties in chiral separation and quantification of enantiomers in the complex environmental matrices, their environmental behavior study has been limited. Enantioselective biodegradation and ecotoxicity of chiral PPCPs tend to make their potential environmental behavior and risk more complicated. Recently, enantiomeric selectivity of chiral PPCPs in environment has gradually caused attention of environmental researchers in developed countries, such as Europe, North America and Japan. Effort has been devoted in studying enantiomeric selectivity of environmental behavior and effect about chiral PPCPs. However, in China, there are very few related studies. It is necessary to carry out more related studies. Consequently, this paper reviews chiral signature of PPCPs, analytical methods, environment behavior and effect selectivity of chiral PPCPs, as well as their potential application in pollution source apportionment. Limitation of current research on environmental behavior and effect of chiral PPCPs is also discussed. The prospect of environmental study on chiral PPCPs in the future is also proposed.

Contents
1 Introduction
2 Manufacture and use of chiral pharmaceuticals
3 Chiral signature of PPCPs
4 Analytical methods of chiral PPCPs
5 Occurrence and environment behavior of chiral PPCPs
6 Toxicological effects of chiral PPCPs
7 Application in source analysis
8 Conclusion and outlook