Food safety is the foundation of safeguarding human health and improving the quality of human life. At the same time, because of the phased development of our economy and society, food safety issues are increasingly exposed in China. At present, there are many problems in the area of food safety detection, including few detection methods, immature rapid detection methods, especially the absence of ultratrace analytical techniques leading to low detection sensitivity. Signal amplification technology provides a possible way to solve those problems. The combination of signal amplification technology and traditional detection methods is gradually attracting more attention because of its applications in the trace detection of heavy metal, biotoxin/chemical toxins, microorganism and illegal additives in foodstuffs. This review introduces four kinds of signal amplification technology and the applications and development tendency in the area of food safety detection. The emphasis and prospect of the development of signal amplification technology in this area are put forward.
Contents
1 Introduction
2 Signal amplification technology
2.1 Signal amplification technology of biotin-avidin system
2.2 Signal amplification technology of enzymatic catalysis
2.3 Signal amplification technology based on nanomaterials
2.4 Nucleic acid amplification
3 The application of signal amplification technology in the area of food safety detection
3.1 Heavy metals detection
3.2 Biotoxins/chemical toxins detection
3.3 Microorganism detection
3.4 Illegal additives detection
3.5 Detection of genetically modified food
4 Conclusion and outlook