Organosilicon materials as a novel class of functional materials with unique properties have become one of the most important research fields in chemistry and material sciences. The present review summarizes novel synthetic methodologies, including alkynyl-azide cycloaddition reaction, thiol-ene reaction and amine-ene Michael addition reaction, for organosilicon synthesis. In particular, the advantages of these strategies and their applications in novel functional organosilicon compounds, organosilicon polymers and organosilicon elastomers are introduced. Finally, the trend and future prospects of novel synthetic strategies for organosilicon synthesis will be presented.