The Bonding Strength and Stability Between Hydroxyapatite Coating and Titanium or Titanium Alloys
Qiaoxia Lin , Meng Yin , Yan Wei , Jingjing Du , Weiyi Chen , Di Huang
Progress in Chemistry ›› 2020, Vol. 32 ›› Issue (4) : 406 -416.
Titanium (Ti) and Ti alloys have been the main clinical application materials for bone and dental implants due to their excellent mechanical properties and good biocompatibility. However, it is not easy to achieve rapid osseointegration with surrounding bone tissues because of the biological inertia of titanium materials. Therefore, the biological activity of implant surface is further required. Hydroxyapatite (HA) is the main inorganic component of human bones and teeth, which has good bioactivity and biocompatibility. But restricted by its own brittleness, HA is often used as a coating material to cover the surface of Ti substrates to improve the biological activity of implants. However, the problems of weak bonding strength between coating and substrate and poor mechanical stability of coating have been the main factors limiting the wide clinical applications of HA coated titanium implants. From the aspects of coating structure, composition and preparation method, the research status and development trend of improving the interface bonding strength between Ti substrate and HA coating at home and abroad are summarized, which could provide a reference for the preparation and application of high-performance titanium implants.
1 Introduction
2 Structural design
2.1 Interface roughening
2.2 Interface nanocrystallization
2.3 Interface gradient design
3 Composition design
3.1 Inorganic ion addition
3.2 Metal and bioceramic addition
3.3 Other
4 Preparation
4.1 High-temperature preparation
4.2 Low-temperature preparation
4.3 Composite preparation
5 Conclusion and outlook
titanium implant / HA coating / bonding strength / stability
The work was supported by the National Natural Science Foundation of China(11632013, 11502158, 11802197, 11902214)
the International Cooperation Project Foundation of Shanxi Province(201803D421060)
the Natural Science Foundation for Young Scientist of Shanxi Province(201801D221439)
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