Oxygen evolution reaction(OER) is a crucial half-reaction of energy storage and transfer technologies, such as water splitting, CO₂ reduction reaction, and rechargeable metal-air batteries. NiFe layered double hydroxide(NiFe-LDH) has been considered as one of the most promising OER catalysts due to its unique layered structure, high performance, and low cost. However, it is limited by the poor conductivity and insufficient exposure to active sites. Therefore, an efficient modification method can greatly improve the electrocatalytic performance of NiFe-LDH. In this review, several typical modification methods are reviewed in detail, including defects introducing, exfoliating, elements doping, surface decorating, and in-situ growing. These methods can develop the intrinsic activity of NiFe-LDH effectively by exposing more reactive sites, increasing the conductivity, and reducing the kinetic energy barrier. Finally, the challenges and opportunities about modifications of NiFe-LDH are discussed.