The research of polymer condensed state(PCS) is an important content of polymer science. As well known, the PCS formation mechanism can impact on the macroscopic physical properties of PCS, and these related results are systematically summarized and built. However, a lot of researches are reported in respect of PCS chemical properties, few systematic induction and summary work is reported which can help scientists explore the relationships and scientific laws of PCS and its chemical properties. In this review, some representative researches of PCS chemical property are systematically summed up and summarized, and divided into three major contents. These three research contents are included that:(1) the impact of polymer structure chemistry on PCS,(2) the impact of PCS on chemical reactions based on 3^rd polymer structural level, and(3) the impact of PCS on chemical reactions based on the higher polymer structural level. Focusing on these contents, we analyzes and discusses the chemical problems of PCS through a lot of reported research work. We hope the further research of PCS can be developed by the point of chemistry, and we also hope do some contributions to the development of PCS by this paper.