High-entropy metal-organic frameworks （HE-MOFs） integrate the high configurational entropy effect of multi-metal solid solutions with the structural tunability of metal-organic frameworks， achieving uniform distribution and synergistic coupling of multiple metal components within a single lattice. This enables the construction of diverse coordination environments， continuously adjustable electronic structures， abundant and highly dispersed active sites， as well as enhanced thermodynamic stability. These characteristics endow HE-MOFs with significant application potential in various catalytic applications. We first introduce the fundamental concepts， configurational entropy criteria， and key physicochemical properties of HE-MOFs. Subsequently， we systematically summarize representative synthesis strategies and further outline functional material derivatization approaches. We then focus on the research progress of HE-MOFs and their derivatives in electrocatalysis， thermocatalysis， and photocatalysis， exploring the structural-performance relationships between framework pore architecture advantages， multi-metal synergistic effects， and entropy-induced electronic structure modulation through typical reaction systems. Finally， we summarize key challenges and future development directions for HE-MOFs catalytic systems from perspectives such as rational catalyst design， reaction mechanism investigation， and application expansion.

Contents

1 Introduction

2 Definition and properties of HE-MOFs

3 Synthesis of HE-MOFs and their derivatives

3.1 Synthesis of HE-MOFs materials

3.2 Synthesis of HE-MOFs derivatives

4 Electrocatalytic applications of HE-MOFs and their derivatives

4.1 Electrochemical oxidation reactions

4.2 Electrochemical reduction reactions

5 Thermocatalytic applications of HE-MOFs and their derivatives

5.1 CO₂ cycloaddition

5.2 Catalytic transfer hydrogenation

5.3 Volatile organic compounds elimination

5.4 Aerobic oxidation of alcohols

5.5 Hydrolysis of ammonia borane

6 Photocatalytic applications of HE-MOFs and their derivatives

7 Conclusions